Chumbe-Mendoza A.^1,2, Izquierdo-Lara R.^1,2, Tataje-Lavanda L.¹, Gonzales Rosa², Gribillero Giovana², Gónzales Armando², Fernández-Díaz M.¹ , Icochea-D’Arrigo E.^1,2.
¹FARVET, Research and Development Laboratories, Ica, Peru. ²Avian Pathology Laboratory, National University of San Marcos, School of Veterinary Medicine, San Borja, Lima, Peru

ABSTRACT

The Newcastle disease virus (NDV) which is also known as Avian paramyxovirus 1 causes Newcastle disease (APMV-1). The objective of this study was to characterize seven NDV isolated (2004-2015) from different regions of Peru by pathogenicity studies and phylogenetic analyses.

Of the seven isolates, six reports of intracerebral pathogenicity index (IPIC) were between 1.75 and 1.88 (velogenic), and the remaining virus have an ICPI of 0.00 (lentogenic). The phylogenetic analyses classified all isolates in class II of APMV-1. Within genotype XII, the new subtypes XIIa (in South America) and XIIb (in China) and possibly two clades were identified within the genotype XIIa. All the velogenic viruses from Peru belong to subgenotype XIIa. These results confirm the presence of genotype XII in Peru and this is the prevailing genotype currently circulating.

To Access the original article, check the following link: https://www.ncbi.nlm.nih.gov/pubmed/28301239